February 4, 2023
Press Release

Finding the right physician is the first step to cure blood diseases

City Reporters Web Desk
Read Time:4 Minute, 33 Second

New Delhi (India), December 13: Bone Marrow Transplantation (BMT) from a donor (Allogeneic BMT) is possibly the most challenging procedure in modern medicine, which has evolved over the last 50 years, curing millions of patients suffering from blood diseases. Both malignant (leukemia/lymphoma/myeloma) and non-malignant (thalassemia/sickle cell anemia/aplastic anemia/ primary immunodeficiencies) however, the success of BMT is incumbent upon finding successful immunological compatibility between the patient and the donor- called matching of HLA or immunological signature, which is inherited from the parents and varies from person to person. There is a 25% chance of two siblings being completely HLA-matched with each other, which basically means that 3 out of 4 patients requiring a BMT would not find a compatible donor.

The question often asked is why an unrelated third person cannot be the donor! The answer lies in the fact that the immunological signature or HLA is extremely variable, and the chance of 2 random persons to match with each other is less than one in a million.  While this problem has been largely addressed in Europe and America, for the Caucasian people, with the creation of large unrelated donor registries, where 3 out of 4 Caucasians can find a completely HLA-Matched Unrelated Donor (MUD). This is large because of the very conserved genetic pool of the population, which is not true for a country like India, where thousands of different ethnic races inhabit. The solution for such patients lies in using HLA half-matched or Haploidentical family donors (not unrelated). Haploidentical BMT is one of the most difficult forms of BMT, and no Indian centre performed such transplants in 2010, when Dr Suparno Chakrabarti first initiated Haploidentical BMT program in India.

Dr Suparno Chakrabarti, an alumnus of PGI, Chandigarh, who initiated the Clinical Hematology program at the institute in 1995, returned to India in 2010. He had left for the UK in 1998 and spent 12 years in both clinical and basic research in the field of BMT, initially as a Research Fellow and subsequently as a faculty. Several paradigm shifts happened in the field of BMT during this time, and Dr Chakrabarti made an immense contribution to the field with several path-breaking research. However, his yearning to contribute to his own country brought him back to India. The last ten years were no less significant in terms of his contribution to the field of BMT and immunology. Dr Sarita Rani Jaiswal joined him in 2011 as a trainee at a premier healthcare centre in Kolkata, where the first BMT Centre of eastern India was created.

Dr Chakrabarti had an enormous task in hand, having initiated the most difficult type of BMT for the first time in India, with little support from the institution and otherwise. He was criticized by many at that time for indulging in such a high-risk procedure. But the initial cohort of patients all had very advanced blood cancers without any other treatment options. Dr Sarita Jaiswal trained under him for 3 years before going abroad and training under the pioneers in the field of Haploidentical BMT in Italy and Seattle, USA.

In view of an indifferent attitude of administration, colleagues and the Bengali population overall, Dr Chakrabarti decided to move his base to Delhi. Dr Sarita Jaiswal, being true to the mission of her mentor, joined him at Dharamshila (Narayana) Hospital in 2014, where Dr Suversha Khanna, the founder-promoter of the hospital and Mr Anil Kumar, the outgoing President of the trust, helped them create a true ecosystem for flourishing in both clinical and basic research.

With only 10-20% survival for Haploidentical BMT in 2012-13, Dr Chakrabarti and Dr Jaiswal invested in extensive research along with the clinical work in Delhi. The rest is now history. Currently, in over 150 Haploidentical BMT carried out between 2015-2021, the survival stands at over 80% in both malignant and non-malignant disorders. Dr Jaiswal had made oral presentations every year between 2015-2021 in scientific conferences in Europe and USA. Their innovations in the field of Haploidentical BMT had researchers in the USA adapt their approach. While this has not been an easy journey, the will, dedication, and honesty paid off at the end.

Both Dr Jaiswal and Dr Chakrabarti rue about the fact that only a handful patients are benefitting from their path-breaking work. Most of the country remains ignorant about the scientific breakthroughs which are happening in their own backyard. They do not have the academic, financial, or political patronage to leverage their achievements for the benefit of the millions who need it. Despite all these limitations, they have not given up. In the memory of his late mother, Dr Chakrabarti started the MANASHI CHAKRABARTI FOUNDATION, which was aimed at supporting research and treatment for children with Blood Diseases. They have initiated a Comprehensive Care Centre for Thalassemia and Sickle Cell Anemia at Dharamshila Narayana Hospital. They have been joined in their endeavour by Dr Nivedita Singh, an administrator by profession, who had been a part of their journey through the rough times. Many young doctors have also joined hands to form a platform called BLOODSRUS, under the auspices of MCF, where they are ready to provide comprehensive service for blood diseases to all those who have been deprived of such care until now. The country and its people should utilise this opportunity and grab the change from overwhelming private and indifferent public healthcare.

About Post Author

City Reporters Web Desk

[email protected]
https://cityreporters.in
Happy
Happy
0 %
Sad
Sad
0 %
Excited
Excited
0 %
Sleepy
Sleepy
0 %
Angry
Angry
0 %
Surprise
Surprise
0 %
0 0
In

Average Rating

5 Star
23%
4 Star
15%
3 Star
8%
2 Star
38%
1 Star
15%
2.90
(Add your review)

143 thoughts on “Finding the right physician is the first step to cure blood diseases”

  2. Thank you for every other informative website. Where else may just I
    am getting that type of information written in such a perfect manner?
    I have a undertaking that I’m just now working on, and I’ve been on the look
    out for such information.

  4. Hello there, I do think your site could possibly be having browser compatibility issues.
    When I take a look at your site in Safari, it looks
    fine however, when opening in IE, it’s got some overlapping issues.

    I merely wanted to give you a quick heads up! Besides that, great blog!

  6. I will immediately grab your rss feed as I can not to find your e-mail subscription link
    or e-newsletter service. Do you have any? Please let me know
    in order that I may just subscribe. Thanks.

  9. Hello, Neat post. There is a problem together with your web site in web explorer, might test this?
    IE still is the marketplace leader and a good
    component of folks will miss your great writing
    due to this problem.

  11. Today, I went to the beach with my children. I found a sea shell and gave it to my 4
    year old daughter and said “You can hear the ocean if you put this to your ear.” She placed the shell
    to her ear and screamed. There was a hermit crab inside and it pinched her ear.
    She never wants to go back! LoL I know this is completely off topic but
    I had to tell someone!

  12. Write more, thats all I have to say. Literally, it seems as though
    you relied on the video to make your point. You obviously
    know what youre talking about, why waste your intelligence on just posting videos to your weblog when you could be giving us something informative to read?

  13. I just like the valuable information you provide for your articles.
    I’ll bookmark your weblog and test once more right here frequently.
    I’m moderately sure I will learn lots of new stuff right here!
    Good luck for the following!

  14. Its like you read my mind! You seem to know a lot about this, like you wrote the book in it or something. I think that you can do with some pics to drive the message home a bit, but other than that, this is wonderful blog. A great read. I’ll certainly be back.

  15. Have you given any kind of thought at all with converting your current web-site into French? I know a couple of of translaters here that will would certainly help you do it for no cost if you want to get in touch with me personally.

  16. I wrote down your blog in my bookmark. I hope that it somehow did not fall and continues to be a great place for reading texts.

  17. Abnormal this put up is totaly unrelated to what I was searching google for, but it surely used to be listed at the first page. I suppose your doing one thing proper if Google likes you adequate to place you at the first page of a non similar search.

  18. বাংলা প্রশ্ন উত্তর সাইট তল্লাশি, আজই আপনার সমস্যা নিয়ে প্রশ্ন করুন , অভিজ্ঞ ব্যক্তিগন আপনার প্রশ্নের উত্তর দিয়ে সহযোগিতা করবে । তাছাড়াও অন্যাদের প্রশ্নের উত্তর দিয়ে, জিতে নিন আকর্ষণীয় পুরস্কার । তল্লাশিতে যেকোনো বিষয়ে প্রশ্ন করতে পারেন।।

  19. whoah this weblog is wonderful i like reading your articles. Keep up the good paintings! You already know, many people are looking around for this information, you can help them greatly.

  20. Hey! awesome blog! I happen to be a daily visitor to your site (somewhat more like addict 😛 ) of this website. Just wanted to say I appreciate your blogs and am looking forward for more!

  28. I know this is not exactly on topic, but i have a blog using the blogengine platform as well and i’m having issues with my comments displaying. is there a setting i am forgetting? maybe you could help me out? thank you.

  35. The post is absolutely great! Lots of great info and inspiration, both of which we all need! Also like to admire the time and effort you put into your blog and detailed information you offer! I will bookmark your website!

  36. I cannot thank you more than enough for the blogposts on your website. I know you set a lot of time and energy into these and truly hope you know how deeply I appreciate it. I hope I’ll do a similar thing person sooner or later.

  45. I dont think I’ve read anything like this before. So good to find somebody with some original thoughts on this subject. cheers for starting this up. This blog is something that is needed on the web, someone with a little originality.

  56. I just couldn’t leave your website before suggesting that I really enjoyed the usual information an individual supply on your visitors? Is gonna be back often in order to investigate cross-check new posts

  66. Dignity Educational CNA School Consultants offer a variety of services including curriculum writing, school catalog preparation, clinical externship contracts preparation, business plan writing, school policies preparation, student handbooks, and provide some other needed forms. We stick with you through approval and 6 months after, depending on your package. Dignity Educational Consulting helps our clients to start up nursing assistant schools in the following 50 states: Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming.

  68. I concur with your conclusions and will eagerly look forward to your future updates. The usefulness and significance is overwhelming and has been invaluable to me!

  71. Thanks for some other great post. Where else may anybody get that kind of information in such an ideal method of writing? I’ve a presentation next week, and I am at the look for such information.

  75. Hello this is a wonderful write-up. I’m going to e mail this to my friends. I came on this while searching on yahoo I’ll be sure to come back. thanks for sharing.

  83. However, it is virtually all done with tongues rooted solidly in cheeks, and everyone has absolutely nothing but absolutely love for his or her friendly neighborhood scapegoat. The truth is, he is not just a pushover. He is basically that special variety of person strong enough to take all of that good natured ribbing for exactly what it is.

  84. I dont think I’ve read anything like this before. So good to find somebody with some original thoughts on this subject. cheers for starting this up. This blog is something that is needed on the web, someone with a little originality.

  88. Good site! I truly love how it is easy on my eyes it is. I am wondering how I might be notified when a new post has been made. I’ve subscribed to your RSS which may do the trick? Have a great day!

  90. I dont think I’ve read anything like this before. So good to find somebody with some original thoughts on this subject. cheers for starting this up. This blog is something that is needed on the web, someone with a little originality.

  126. you’re in reality a just right webmaster. The web site loading velocity is incredible. It sort of feels that you’re doing any distinctive trick. In addition, The contents are masterpiece. you’ve performed a great process on this topic!

  129. American Crisis Prevention and Management Association Management of Assaultive Behavior (MAB) certification course can be conveniently done online or in the classroom. Also known as AB 508 certification training, mab certification online or managing aggressive behavior is a training for healthcare professionals, teachers, law enforcement agents., and other individuals that come in contact with potential aggression. Nurses, doctors and other healthcare professionals receive CE credits at the end of the course. Enroll now at https://crisispreventionmanagement.com/mab-management-of-assaultive-behavior

  131. I definitely wanted to construct a brief remark in order to express gratitude to you for all the great ways you are placing at this site. My long internet search has finally been paid with reasonable facts and strategies to write about with my family and friends. I ‘d point out that many of us site visitors are truly endowed to dwell in a magnificent website with so many special people with beneficial solutions. I feel rather happy to have come across the website page and look forward to so many more awesome minutes reading here. Thanks again for everything.

  135. Excellent goods from you, man. I’ve understand your stuff previous to and you are just too great. I really like what you have acquired here, really like what you are stating and the way in which you say it. You make it enjoyable and you still care for to keep it wise. I can not wait to read much more from you. This is really a terrific web site.

  136. Together with the whole thing which seems to be developing within this particular subject matter, all your opinions are actually quite stimulating. Having said that, I appologize, because I do not give credence to your whole strategy, all be it exciting none the less. It would seem to everybody that your comments are not completely justified and in actuality you are generally yourself not really fully certain of the argument. In any case I did appreciate reading it.

  138. I in addition to my pals were examining the best information and facts found on your site and so then came up with a horrible suspicion I had not thanked you for those techniques. My women ended up consequently very interested to study them and have in effect truly been loving these things. Thanks for turning out to be very accommodating and for pick out certain tremendous ideas most people are really wanting to be aware of. Our sincere apologies for not saying thanks to you sooner.

  143. I am curious to find out what blog platform you are working with? I’m having some small security issues with my latest site and I’d like to find something more safeguarded. Do you have any recommendations?

Leave a Reply

Your email address will not be published.

Previous post Simpliv Learning Expands to More than 5500+ Courses a Year
Next post Tea time group launched 100% biodegradable paper cups in Nationwide Awards 2021- Hyderabad

More Stories

Recent Post

Top Category

Business

Lifestyle

National

Entertainment